Diana Levine claimed that, as a result of being injected with the Wyeth antinausea drug Phenergan as part of migraine treatment, she developed gangrene and had to have part of her arm amputated. A Vermont jury determined that Levine’s injury would not have occurred if Phenergan’s label included an adequate warning, and it awarded $7.4 million in damages, which the court later reduced. Arguing that Levine’s claims were pre-empted by federal law because Phenergan’s labeling had been approved by the Food and Drug Administration (FDA), Wyeth appealed the case all the way to the U.S. Supreme Court, which affirmed the award in March 2009.