In February 2012, the U.S. Drug Enforcement Administration (DEA) issued an Immediate Suspension Order (ISO) at Cardinal Health, a pharmaceutical wholesale distributor in Lakeland, Florida, and two of its CVS Pharmacy customers. The ISO against Cardinal Health’s Lakeland distribution center alleged that it failed to maintain effective controls against the diversion of controlled substances – oxycodone – into other than legitimate medical, scientific, and industrial channels, and that Cardinal Health failed to conduct due diligence to ensure that the controlled substances were not diverted into other than legitimate channels. In December 2007, the DEA issued an ISO at the same location due to its distribution of hydrocodone to “rogue” internet pharmacies. In May 2012, the DEA entered into a settlement agreement with Cardinal Health that suspended for two years its Lakeland facility’s ability to sell controlled-substance medications.